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Users believe that this time-off period helps to minimise side-effects. They can also cause men to lose their hair, develop acne and shrink testicles. Unfortunately, as supplement sales skyrocketed, so did marketing hyperbole. During the 1970s, the use of anabolic steroids was openly discussed, partly due to the fact they were legal. Bodybuilders often note that these doses greatly enhance the performance boost offered by anabolic steroids, and for the most part, the two work synergistically together without any increased risk of side effects. Finally, nodular regenerative hyperplasia of the liver has been described in rare patients on long term anabolic or androgenic steroids. Some professional baseball players, cyclists, and track stars have been accused of — and in some cases have admitted to — using steroids to give them an edge competitively.

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